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. 2016 Nov 24;6:37467. doi: 10.1038/srep37467

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Copyright © 2016, The Author(s)

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2K1C rats had a lower level of Cu/Zn-SOD and a higher level of p^47phox compare with SHAM rats. ExT enhanced the expression of Cu/Zn-SOD and attenuated the expression of p^47phox. (a) Representative immunoblot; (b) Densitometric analysis of protein expression of Cu/Zn-SOD and p^47phox in the PVN in different groups. Cu/Zn-SOD: copper/zinc superoxide dismutase; PVN: hypothalamic paraventricular nucleus; 2K1C: two-kidney, one-clip; ExT: exercise training; Sed: sedentary. Values are expressed as means ± SE. *P < 0.05 vs SHAM groups (SHAM+ Sed or SHAM + ExT); ^†P < 0.05 2K1C + ExT vs 2K1C + Sed.