Table 3. Logistic regression analysis of T2DM_CAD vs control subjects.
Factor | Univariate | Multivariate | Model 1 (Unadjusted) | Model 2 (Adjusted) | ||||
---|---|---|---|---|---|---|---|---|
OR (95% CI) | P value | OR (95% CI) | P value | OR (95% CI) | P value | OR (95% CI) | P value | |
Age | 1.01 (1.04–1.15) | 0.001 | 1.114 (1.024–1.212) | 0.0118 | ||||
Sex (female) | 0.27 (0.9–0.81) | 0.019 | 0.326 (0.040–2.666) | 0.2960 | ||||
BMI | 0.98 (0.88–1.073) | 0.602 | ||||||
HbA1c (%) | 23.31 (3.91–138.99) | 0.0005 | 1000 (0.005–1000) | <0.0001 | ||||
FBS (mg/dl) | 1.07 (1.04–1.10) | <0.0001 | 1.25 (0.89–1.74) | 0.0001 | ||||
Systolic BP (mmHg) | 1.04 (1.01–1.07) | 0.023 | ||||||
Diastolic BP (mmHg) | 1.06 (0.99–1.12) | 0.067 | ||||||
Creatinine (mg/dl) | 20.49 (2.42–173.36) | 0.0056 | 259.85 (7.48–1000) | 0.0021 | 32.932 (0.459–1000) | 0.1089 | ||
eGFR (ml/min/1.72 m2) | 0.98 (0.95–0.99) | 0.012 | ||||||
Uric acid (mg/dl) | 0.90 (0.67–1.22) | 0.493 | ||||||
CK-MB (u/l) | 5.83 (2.17–15.68) | 0.0005 | 9.903 (0.714–137.319) | 0.0875 | ||||
Apo-B (mg/dl) | 6.09 (2.39–15.48) | 0.0001 | 0.755 (0.072–8.340) | 0.8335 | ||||
Smoking history (years) | 1.16 (0.49–2.77) | 0.739 | 1.281 (0.255–6.440) | 0.7636 | ||||
Alcoholic history (years) | 1.02 (0.97–1.08) | 0.349 | ||||||
Family history (years) | 0.95 (0.92–0.98) | 0.0003 | ||||||
D3 (ng/ml) | 0.94 (0.88–1.003) | 0.059 | ||||||
25(OH)D3 (ng/ml) | 0.88 (0.83–0.93) | <0.0001 | ||||||
1,25(OH)D3 (ng/ml) | 0.354 (0.22–0.56) | <0.0001 | ||||||
D2 (ng/ml) | 0.88 (0.82–0.94) | <0.002 | ||||||
25(OH)D2 (ng/ml) | 0.92 (0.80–1.05) | 0.211 | ||||||
1,25(OH)D2 (ng/ml) | 0.39 (0.23–0.67) | 0.0006 | ||||||
Total 25(OH)D (ng/ml) | 0.91 (0.86–0.95) | <0.0001 | 0.951 (0.899–1.005) | 0.074 | 0.960 (0.902–1.022) | 0.1986 | ||
Total 1,25(OH)D (ng/ml) | 0.503 (0.37–0.68) | <0.0001 | 6.04 (0.011–19.20) | 0.0017 | 0.572 (0.359–0.912) | 0.019 | 0.460 (0.242–0.874) | 0.0177 |
Model 1: unadjusted, Model 2: adjusted for age, sex, smoking history, alcoholic history and family history of diabetes.