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. 2016 Nov 24;6:37631. doi: 10.1038/srep37631

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Copyright © 2016, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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Cells were treated with allyl-CN (A), 3-but-CN (B), benzyl-CN (C) and 4-MTB-CN (D) for 72 hours and viability was analyzed using WST-1 assay. Bars are mean + SEM, n = 3. *P ≤ 0.05, asterisks indicate a significant difference between the sample and the solvent control: medium. CYP2E1: HepG2-CYP2E1, vector: HepG2-vector.