Table 1. Correlation between GNA13 expression and clinical and pathological characters in HCC patients.
| Variable | All cases N = 246 (%) | Low GNA13 expression N = 98 (%) | High GNA13 expression N = 148 (%) | χ2 | P value |
|---|---|---|---|---|---|
| Age (years)a | 0.329 | 0.566 | |||
| ≤49 | 121 (49.2) | 46 (38.0) | 75 (62.0) | ||
| >49 | 125 (50.8) | 52 (41.6) | 73 (58.4) | ||
| Mean ± SD (49.4 ± 12.1) | |||||
| Gender | 1.216 | 0.270 | |||
| Female | 21 (8.5) | 6 (28.6) | 15 (71.4) | ||
| Male | 225 (91.5) | 92 (40.9) | 133 (59.1) | ||
| HBsAg | 0.665 | 0.415 | |||
| Yes | 216 (87.8) | 84 (38.9) | 132 (61.1) | ||
| No | 30 (12.2) | 14 (46.7) | 16 (53.3) | ||
| AFP (ng/ml) | 1.981 | 0.159 | |||
| <200 | 112 (45.5) | 50 (44.6) | 62 (55.4) | ||
| ≥200 | 134 (54.5) | 48 (35.8) | 86 (64.2) | ||
| Liver cirrhosis | 3.413 | 0.065 | |||
| Yes | 191 (77.6) | 82 (42.9) | 109 (57.1) | ||
| No | 55 (22.4) | 16 (29.1) | 39 (70.9) | ||
| Tumor size (cm) | 0.923 | 0.337 | |||
| ≤5 | 89 (36.2) | 39 (43.8) | 50 (56.2) | ||
| >5 | 157 (63.8) | 59 (37.6) | 98 (62.4) | ||
| Tumor multiplicity | 8.400 | 0.004* | |||
| Single | 202 (82.1) | 89 (44.1) | 113 (55.9) | ||
| Multiple | 44 (17.9) | 9 (20.5) | 35 (79.5) | ||
| Pathological grade | 2.705 | 0.439 | |||
| Well (I) | 20 (8.1) | 11 (55.0) | 9 (45.0) | ||
| Moderate (II) | 107 (43.5) | 44 (41.1) | 63 (58.9) | ||
| Poor (III) | 114 (46.4) | 41 (36.0) | 73 (64.0) | ||
| Undifferentiated (IV) | 5 (2.0) | 2 (40.0) | 3 (60.0) | ||
| TNM stage | 14.644 | 0.002* | |||
| I | 160 (65.0) | 77 (48.1) | 83 (51.9) | ||
| II | 18 (7.3) | 6 (33.3) | 12 (66.7) | ||
| III | 56 (22.8) | 11 (19.6) | 45 (80.4) | ||
| IV | 12 (4.9) | 4 (33.3) | 8 (66.7) | ||
| BCLC stage | 11.295 | 0.010* | |||
| 0 | 9 (3.7) | 6 (66.7) | 3 (33.3) | ||
| A | 171 (69.5) | 76 (44.4) | 95 (55.6) | ||
| B | 38 (15.4) | 8 (21.1) | 30 (78.9) | ||
| C | 28 (11.4) | 8 (28.6) | 20 (71.4) | ||
| Vascular invasion | 2.514 | 0.113 | |||
| Yes | 18 (7.3) | 4 (22.2) | 14 (77.8) | ||
| No | 228 (92.7) | 94 (41.2) | 134 (58.8) | ||
apatients were divided according to the median age; AFP: alpha-fetoprotein; HBsAg: hepatitis B surface antigen.
*P < 0.05.