Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 Nov 24;6:37891. doi: 10.1038/srep37891

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2016, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

PMC Copyright notice

(a) Sucrose density gradient ultracentrifugation of different tHBcAg nanoparticle packaging samples. tHBcAg nanoparticles containing doxorubicin (DOX) were separated by ultracentrifugation on sucrose gradients (8–40%). The total protein in each fraction (400 μL) was determined by a Bradford assay. Packaging of DOX with tHBcAg nanoparticles (tHBcAg-DOX), tHBcAg nanoparticles loaded with PAA-DOX (tHBcAg-PAA-DOX), and FA-conjugated tHBcAg nanoparticles using the nanoglue and loaded with PAA-DOX (FA-N-tHBcAg-PAA-DOX). tHBcAg nanoparticles (tHBcAg) were used as a negative control. (b) Electron micrographs of the tHBcAg nanoparticles from different packaging samples. The samples are labelled on top of the micrographs. All the samples assembled into spherical structures. White bars indicate 50 nm.