[Table/Fig-5]:
Serotonin staining intensity in relation to clinicopathologic features of psoriasis cases.
| Variable | Serotonin staining intensity | Test of significance and p-value | |||
|---|---|---|---|---|---|
| Negative | Mild | Moderate | Strong | ||
| Age (ys) | |||||
| X±SD | 40±14.08 | 37.2±12.39 | 35.3±12.45 | 36.5±12.2 | K= 0.4 |
| Median | 39 | 35 | 35 | 36 | p= 0.93 |
| Mean rank | 13.8 | 13.3 | 11.95 | 11.25 | |
| Gender | |||||
| Male | 4(80%) | 3(60%) | 5(50%) | 3(75%) | χ2 = 1.6 |
| Female | 1(20%) | 2(40%) | 5(50%) | 1(25%) | p= 0.65 |
| Duration (months) | |||||
| X±SD | 4± 2.64 | 5.2± 2.8 | 5.1± 4.4 | 4.5± 3.38 | K= 1.6 |
| Median | 3.66 | 4.5 | 3.66 | 3 | p= 0.6 |
| Mean rank | 12.1 | 15.4 | 12.5 | 4.38 | |
| PASI score | |||||
| X±SD | 83.33±5.7 | 35.4±12.8 | 32±12.9 | 31.2±7.5 | K= 1.5 |
| Median | 38 | 35 | 30 | 31.66 | p= 0.6 |
| Mean rank | 15.5 | 13.4 | 11.2 | 10.88 | |
| Nail affection | |||||
| Present | 4(80%) | 0(0%) | 3(30%) | 1(25%) | χ2 = 7.75 |
| Absent | 1(20%) | 5(100%) | 7(70%) | 3(75%) | p= 0.055* |
| Scaly scalp | |||||
| Present | 1(20%) | 2(40%) | 3(30%) | 1(25%) | χ2 = 0.52 |
| Absent | 4(80%) | 3(60%) | 7(70%) | 3(75%) | p= 0.91 |
| Parakeratosis | |||||
| Present | 2(40%) | 2(40%) | 5(50%) | 2(50%) | χ2 = 0.23 |
| Absent | 3(60%) | 3(60%) | 5(50%) | 2(50%) | p= 0.97 |
| GCL | |||||
| Thin/focally absent | 4(80%) | 4(80%) | 2(20%) | 3(75%) | χ2 = 8.9 |
| Totally absent | 1(20%) | 1(20%) | 8(80%) | 1(25%) | p= 0.044* |
| Acanthosis | |||||
| Mild/sparse | 2(40%) | 4(80%) | 8(80%) | 2(50%) | χ2 = 3.3 |
| Marked | 3(60%) | 1(20%) | 2(20%) | 2(50%) | p= 0.34 |
| Epidermal inflammation | |||||
| Mild/sparse | 3(60%) | 3(60%) | 1(10%) | 2(50%) | χ2 = 5.6 |
| Marked | 2(40%) | 2(40%) | 9(90%) | 2(50%) | p= 0.13 |
| Microabcesses | |||||
| Present | 1(20%) | 2(40%) | 2(20%) | 1(25%) | χ2 = 0.8 |
| Absent | 4(80%) | 3(60%) | 8(80%) | 3(75%) | p= 0.85 |
| Dermal inflammation | |||||
| Mild/sparse | 3(60%) | 2(40%) | 6(60%) | 0(0%) | χ2 = 4.64 |
| Marked | 2(40%) | 3(60%) | 4(40%) | 4(100%) | p= 0.19 |
| Dilated capillaries/tortous BVs | |||||
| Present | 2(40%) | 4(80%) | 5(50%) | 4(100%) | χ2 = 4.8 |
| Absent | 3(60%) | 1(20%) | 5(50%) | 0(0%) | p= 0.18 |
χ2: chi square test; K: Kruskal Wallis test; X±SD: mean±Standard deviation; GCL: granular cell layer.*: significant