[Table/Fig-4]:

Studies depicting effects of infliximab in treatment of RAS.

STUDY	SUBJECTS	TREATMENT	EFFECTS
Ryu HJ et al., (2014) [4]	Four patients with recurrent oral ulcers resistant to conventional treatments.	A single dose of infliximab was given to the patients; an additional dose was administered in one patient on demand.	A good response was noted in all patients. The effects of infliximab diminished after a few weeks. However, the ulcers were tolerable and an increase steroids or addition of another medication was not required for about 1 year.
Travis S et al., (2001) [40]	Two women with orogenital ulceration associated with Behcet’s disease	For one patient, Infliximab 3mg/kg was given because of an episode of recent sepsis, while in the other 5mg/kg was administered.	Ulcers healed within 10 days.
Almoznino G et al., (2007) [41]	48-year-old woman who had recurrent oral ulcers due to Behcet’s syndrome and was unresponsive to many other medications.	A single dose of Infliximab was given.	Complete remission in the mouth aphthae within 7 days.
Robertson LP et al., (2001) [42]	48-year-old woman who had recurrent oral ulcers due to Behcet’s syndrome and unresponsive to many other medications.	Infliximab 5mg/kg infusion (0, 2 and 6 weeks).	Significant improvement in the oral ulcers was observed after first infusion itself and after the third dose, the patient was completely free from ulcers.
Kaufman I et al., (2005) [43]	Patients with Crohn’s disease and Ulcerative colitis.	Infliximab 5 mg/kg infusion.	Aphthous stomatitis completely responded in all patients after a single infusion.
Bañeros-Rojas P et al., (2015) [44]	24-year-old woman with RAS associated with BD.	Infliximab 5mg/kg/day (0-2-6 weeks and every 8 weeks) and methylprednisolone (1 g/24h).	Fast remission.