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. 2016 Nov 24;17:970. doi: 10.1186/s12864-016-3311-0

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 6 — a. Co-varying reactions clusters identification. Common flux trends (expressed as the normalized difference between the absolute value of fluxes across each growth phase and the following one) for the reactions embedded in each of the 28 clusters. b. The distribution of STRING combined scores among all the genes embedded in each cluster of genes (primary y axis) and the number of genes embedded by each cluster (secondary y axis, red line). The grey line represents the median of the combined score computed for each possible pair of genes in the model