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. 2016 Nov 24;18:272. doi: 10.1186/s13075-016-1170-3

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Drug survival during treatment with etanercept (ETA), adalimumab (ADA) or tocilizumab (TOC); weighted Kaplan-Meier analyses weighted by an inverse probability of treatment estimated by a generalized propensity score. Significant differences were noted, using the Cox proportional hazard model, between the cohorts treated with adalimumab versus etanercept (p < 0.001, hazard ratio 0.60 (0.48–0.75)), adalimumab versus tocilizumab (p = 0.001, hazard ratio 0.21 (0.12 − 0.39)) and tocilizumab versus etanercept (p < 0.001, hazard ratio 2.82 (1.55 − 5.14))