Table 1.

Efficacy of Diclegis® compared to placebo for the treatment of NVP

Study Day	Statistics	PUQE score (mean ± SD) of Diclegis®-treated women	PUQE score (mean ± SD) Placebo-treated women	P-value
Baseline		9.0 ± 2.1	8.8 ± 2.1
Day 3	N	128	123
	Day 3 PUQE score	5.9 ± 2.4	6.7 ± 2.2
	Change from Baseline	−3.1 ± 2.7	–2.1 ± 2.4	0.002
	% Change from Baseline	34.4%	23.9%
Day 4	N	125	120
	Day 4 PUQE score	5.4 ± 2.2	6.3 ± 2.3
	Change from Baseline	–3.6 ± 2.5	–2.5 ± 2.2	<0.001
	% Change from Baseline	40.0%	28.4%
Day 5	N	122	112
	Day 5 PUQE score	5.1 ± 2.2	5.8 ± 2.1
	Change from Baseline	–4.0 ± 2.5	–3.0 ± 2.4	0.006
	% Change from Baseline	44.4%	34.0%
Day 15	N	131	125
	Day 15 PUQE score	4.2 ± 1.9	4.9 ± 2.3
	Change from Baseline	–4.8 ± 2.7	–3.9 ± 2.6	0.006
	% Change from Baseline	53.0%	44.0%

Change in Pregnancy-Unique Quantification of Emesis score from baseline to Days 3, 4, 5 and 15