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. 2016 Nov 24;13:34. doi: 10.1186/s12950-016-0142-3

Fig. 2.

Fig. 2

Effect of metformin with different durations on cytokines in serum and urine of patients with type 2 diabetes. Serum and urine were collected from type 2 diabetic patients treated with metformin for less (n = 71) and more than 1 year (n = 41) for cytokine measurement by ELISA. Data were shown as Mean ± SD. ** P < 0.05, vs metformin (<1 year) group