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. 2016 Nov 24;13:34. doi: 10.1186/s12950-016-0142-3

Table 2.

Comparison of metformin with other drugs on cytokines

Treatment N Serum (pg/ml) Urine (pm/ml)
IL-6 IL-10 TNF-α MCP-1
Metformin 54 11.27 ± 2.56 2.50 ± 0.59 11.26 ± 2.14 111.28 ± 21.06
Gliclazide 44 12.24 ± 2.42 2.55 ± 0.69 10.89 ± 2.26 126.42 ± 28.85**
Acarbose 18 12.99 ± 2.73* 2.19 ± 0.74 12.62 ± 3.17* 114.24 ± 22.86
Repaglinide 36 13.02 ± 2.78** 2.56 ± 0.62 11.36 ± 1.98 123.46 ± 14.30**

*P < 0.05

**P < 0.01, vs metformin