Table 2. Univariate and multivariate analysis of factors associated with overall survival time of patients with nonsmall cell lung cancer.
| Clinical variable | Case number | HR (95% CI) | P Value |
|---|---|---|---|
| Univariate analysis | |||
| miR-101 (Low vs High) | 52/53 | 2.467 (1.528-3.984) | < 0.001 |
| Age (>60 vs ≤60) | 58/47 | 0.896 (0.561-1.430) | 0.646 |
| Gender (Female vs Male) | 38/67 | 0.989 (0.610-1.603) | 0.963 |
| Histological type (SqCC vs A vs Other) | 29/64/12 | 1.179 (0.795-1.749) | 0.413 |
| Differentiation (Moderate+high vs Low) | 45/60 | 0.600 (0.370-0.974) | 0.039 |
| Distant metastasis (M1 vs M0) | 8/97 | 9.939 (4.515-21.879) | < 0.001 |
| T factor (T3+T4 VS T1+T2) | 50/55 | 1.722 (1.073-2.761) | 0.024 |
| Lymph node (N2+N3 vs N0+N1) | 45/60 | 6.612 (3.897-11.219) | < 0.001 |
| Clinical stage (III + IV vs I + II) | 51/54 | 9.842 (5.516-17.560) | < 0.001 |
| multivariate analysis | |||
| miR-101 (Low vs High) | 52/53 | 1.780 (1.033-3.067) | 0.038 |
| Differentiation (Moderate+high vs Low) | 45/60 | 0.834 (0.491-1.415) | 0.501 |
| T factor (T3 + T4 vs T1 + T2) | 50/55 | 1.051(0.625-1.768) | 0.852 |
| Lymph node (N2 + N3 vs N0 + N1) | 45/60 | 0.519 (0.206-1.311) | 0.165 |
| Clinical stage (III + IV vs I + II) | 51/54 | 14.798 (5.113-42.835) | < 0.001 |