Table 1. Smallest regions of overlap found in at least 30% of all immortal descendants analyzed.
GAINS | |||||||||
---|---|---|---|---|---|---|---|---|---|
Chromosome | Start position | End position | Cytoband | Samples (n=) | Crisis (n=) | No crisis (n=) | % Total | % Crisis | % No crisis |
5 | 33485408 | 45972937 | 5p13.3-p11 | 6 | 6 | 0 | 30.00% | 66.67% | 0.00% |
5 | 124833923 | 139945983 | 5q23.2-q31.3 | 8 | 5 | 3 | 40.00% | 55.56% | 27.27% |
5 | 176088956 | 176851727 | 5q35.2-q35.3 | 9 | 6 | 3 | 45.00% | 66.67% | 27.27% |
5 | 176946793 | 179205640 | 5q35.3 | 8 | 6 | 2 | 40.00% | 66.67% | 18.18% |
8 | 47703628 | 48686513 | 8q11.1-q11.21 | 6 | 6 | 0 | 30.00% | 66.67% | 0.00% |
8 | 85579256 | 93417060 | 8q21.2-q22.1 | 6 | 4 | 2 | 30.00% | 44.44% | 18.18% |
8 | 109774071 | 110527427 | 8q23.1 | 6 | 4 | 2 | 30.00% | 44.44% | 18.18% |
8 | 113540571 | 115896284 | 8q23.3 | 7 | 5 | 2 | 35.00% | 55.56% | 18.18% |
8 | 117782567 | 117927576 | 8q24.11 | 7 | 5 | 2 | 35.00% | 55.56% | 18.18% |
8 | 123323854 | 124468697 | 8q24.13 | 8 | 6 | 2 | 40.00% | 66.67% | 18.18% |
8 | 128130585 | 131754948 | 8q24.21-q24.22 | 9 | 7 | 2 | 45.00% | 77.78% | 18.18% |
8 | 137882907 | 140116037 | 8q24.23-q24.3 | 7 | 5 | 2 | 35.00% | 55.56% | 18.18% |
8 | 145785956 | 146005188 | 8q24.3 | 6 | 5 | 1 | 30.00% | 55.56% | 9.09% |
9 | 163131 | 38571787 | 9p24.3-p13.2 | 8 | 3 | 5 | 40.00% | 33.33% | 45.45% |
9 | 71889510 | 141122055 | 9q21.13-q34.3 | 12 | 7 | 5 | 60.00% | 77.78% | 45.45% |
14 | 106410478 | 106512963 | 14q32.33 | 6 | 5 | 1 | 30.00% | 55.56% | 9.09% |
20 | 70580 | 4168304 | 20p13 | 9 | 5 | 4 | 45.00% | 55.56% | 36.36% |
20 | 29833609 | 34687137 | 20q11.21-q11.23 | 17 | 9 | 8 | 85.00% | 100.00% | 72.73% |
20 | 36444066 | 37986609 | 20q11.23-q12 | 16 | 8 | 8 | 80.00% | 88.89% | 72.73% |
20 | 38430006 | 40351587 | 20q12 | 16 | 8 | 8 | 80.00% | 88.89% | 72.73% |
20 | 41617589 | 42924016 | 20q13.12 | 16 | 8 | 8 | 80.00% | 88.89% | 72.73% |
20 | 51151491 | 53396641 | 20q13.2 | 17 | 9 | 8 | 85.00% | 100.00% | 72.73% |
20 | 61153381 | 61863831 | 20q13.33 | 14 | 7 | 7 | 70.00% | 77.78% | 63.64% |
20 | 62208157 | 62654677 | 20q13.33 | 14 | 8 | 6 | 70.00% | 88.89% | 54.55% |
LOSSES | |||||||||
---|---|---|---|---|---|---|---|---|---|
Chromosome | Start position | End position | Cytoband | Samples (n=) | Crisis (n=) | No crisis (n=) | % Total | % Crisis | % No crisis |
2 | 97526630 | 97547543 | 2q11.2 | 8 | 4 | 4 | 40.00% | 44.44% | 36.36% |
2 | 132307267 | 169457945 | 2q21.2-q24.3 | 8 | 4 | 4 | 40.00% | 44.44% | 36.36% |
2 | 239000632 | 239063582 | 2q37.3 | 9 | 5 | 4 | 45.00% | 55.56% | 36.36% |
3 | 64066 | 11848995 | 3p26.3-p25.2 | 13 | 6 | 7 | 65.00% | 66.67% | 63.64% |
3 | 60445746 | 90282056 | 3p14.2-p11.1 | 15 | 7 | 8 | 75.00% | 77.78% | 72.73% |
4 | 3475992 | 3535404 | 4p16.3 | 12 | 4 | 8 | 60.00% | 44.44% | 72.73% |
4 | 45518913 | 49083231 | 4p13-p11 | 6 | 4 | 2 | 30.00% | 44.44% | 18.18% |
4 | 148601450 | 156726238 | 4q31.22-q32.1 | 6 | 3 | 3 | 30.00% | 33.33% | 27.27% |
8 | 360369 | 22021010 | 8p23.3-p21.3 | 6 | 5 | 1 | 30.00% | 55.56% | 9.09% |
8 | 39237438 | 39380595 | 8p11.23 | 6 | 5 | 1 | 30.00% | 55.56% | 9.09% |
12 | 163593 | 38497380 | 12p13.33-q12 | 6 | 3 | 3 | 30.00% | 33.33% | 27.27% |
12 | 38503456 | 53699602 | 12q12-q13.2 | 6 | 3 | 3 | 30.00% | 33.33% | 27.27% |
12 | 61177213 | 85549706 | 12q14.1-q21.32 | 6 | 3 | 3 | 30.00% | 33.33% | 27.27% |
12 | 121285002 | 133779017 | 12q24.31-q24.33 | 7 | 3 | 4 | 35.00% | 33.33% | 36.36% |
13 | 34725259 | 35770047 | 13q13.3 | 11 | 5 | 6 | 55.00% | 55.56% | 54.55% |
16 | 96766 | 1404007 | 16p13.3 | 8 | 4 | 4 | 40.00% | 44.44% | 36.36% |
16 | 29815121 | 29829346 | 16p11.2 | 6 | 3 | 3 | 30.00% | 33.33% | 27.27% |
16 | 78424175 | 78609668 | 16q23.1-q23.2 | 8 | 5 | 3 | 40.00% | 55.56% | 27.27% |
18 | 5988578 | 14978075 | 18p11.31-p11.21 | 7 | 5 | 2 | 35.00% | 55.56% | 18.18% |
18 | 77158676 | 77307340 | 18q23 | 7 | 4 | 3 | 35.00% | 44.44% | 27.27% |
18 | 77628089 | 77670636 | 18q23 | 6 | 3 | 3 | 30.00% | 33.33% | 27.27% |
22 | 16053473 | 17599429 | 22q11.1-q11.21 | 8 | 5 | 3 | 40.00% | 55.56% | 27.27% |
22 | 20293142 | 20306772 | 22q11.21 | 10 | 6 | 4 | 50.00% | 66.67% | 36.36% |
22 | 24341374 | 24406990 | 22q12.1 | 8 | 4 | 4 | 40.00% | 44.44% | 36.36% |
22 | 38470042 | 38507492 | 22q13.1 | 17 | 8 | 9 | 85.00% | 88.89% | 81.82% |
22 | 50613880 | 51218950 | 22q13.33 | 17 | 8 | 9 | 85.00% | 88.89% | 81.82% |