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. 2016 May 13;7(25):37868–37881. doi: 10.18632/oncotarget.9350

Figure 1. Expression of DANCR increases in human prostate cancer tissues and cell lines.

Figure 1

(A) DANCR expresses higher in prostate cancer tissues than in normal controls. NPT-free: Normal prostate tissue free of any pathological alteration (n = 17); NPT: Normal prostate tissue adjacent to tumor (n = 58); Tumor: prostate cancer tissues (n = 64). Data from GEO profiles. (B) Relative expression of DANCR in patients with different Gleason Scores. GSC3: n = 10; GSC4: n = 12; GSC5: n = 8. Data from GEO profiles. (C) Human prostate tissues with Gleason score 7 or above were acquired (n = 12). Epithelial cells were laser-capture micro-dissected and used for real-time PCR analysis. DANCR mRNA levels were quantified and normalized to GAPDH. All data represent matched pairs of cancer and normal adjacent tissue. (D) Relative expression of DANCR in prostate cancer cell lines in comparison with an immortalized normal prostate epithelial cell line. DANCR was examined by RT-qPCR and normalized to GAPDH expression. *p < 0.05.