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. 2016 May 13;7(25):37868–37881. doi: 10.18632/oncotarget.9350

Figure 5. Knockdown of DANCR decreases migration and invasion of prostate cancer cells in vivo.

Figure 5

(A, B) Knockdown of DANCR decreased the number of metastatic foci of CW22Rv1 cells injected by tail vein in nude mice (7 mice in each group), as detected by histological analysis of mouse metastatic tumor tissue. The arrow indicates tumor foci in lung. (C) Knockdown of DANCR increases the expression of TIMP2/3 in the metastatic foci of CW22Rv1 cells injected by tail vein in nude mice, as detected by immunohistochemistry analysis of mouse metastatic tumor tissue. *p < 0.05.