Table 2. Subgroup analysis APC promoter methylation in breast cancer.

	Case		Control		OR [95% CI]	P	I2 (%)	Model
	M	UM	M	UM
Total	815	1258	147	1017	5.92 [3.16, 11.07]	< 0.00001	77	Random
Method
MSP	318	320	33	316	13.38 [4.34, 41.25]	< 0.00001	72	Random
QMSP	497	938	114	728	3.11 [1.72, 5.62]	0.0002	65	Random
Ethnicity
Caucasian	591	941	133	589	3.08 [1.92, 4.96]	< 0.00001	52	Random
non-Caucasian	224	317	14	428	18.75 [4.12, 85.28]	< 0.0001	75	Random
Control type
Blood	231	667	32	495	7.42 [1.55, 35.48]	0.01	89	Random
Tissue	584	600	115	522	4.56 [2.63, 7.90]	< 0.00001	52	Random

M, methylation; UM unmethylation; MSP, Methylation-Specific PCR; QMSP, Quantitative real time Methylation Specific.