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(A) With the addition of Z-VAD-FMK, levels of cleaved Caspase-3 and PARP1 were decreased. (B) Levels of Beclin1, Atg5, Atg7 and LC3-II were decreased after IFN-γ stimulation. However, when IFN-γ was combined with the caspase inhibitor, levels of Beclin1, Atg5, Atg7 and LC3-II were not decreased as determined by the Western Blot test. (C) Summary of the roles of IRF-1 in apoptosis and autophagy.
