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. 2016 May 13;7(25):37979–37992. doi: 10.18632/oncotarget.9365

Table 2. Comparisons of RFSs between different expression groups of each molecule.

Tumor marker Grouping methods
Negative vs. positive groupa Low vs.high expression groupb
Log Rank χ2 P Log Rank χ2 P
CK 0.668 0.414 2.680 0.102
CK19 0.029 0.864 0.035 0.852
GPC3 0.364 0.547 1.423 0.233
AFP 0.417 0.518 1.436 0.231
VEGF 1.472 0.225 0.004 0.951
EGFR 0.587 0.444 0.257 0.612
ERCC1 0.448 0.503 1.955 0.162
RRM1 0.009 0.927 0.088 0.767
TYMS 0.019 0.891 2.622 0.105
BRCA1 0.678 0.410 4.322 0.038
p53 6.740 0.009 0.079 0.778
VIM 0.137 0.711 0.596 0.440
Ki-67 16.589 0.001c 14.268 0.001c
IRF-1 5.167 0.023 1.358 0.244
a

Immunochemical results grouping: “−” was included in negative group; “+” or a higher expression was included in positive group.

b

Immunochemical results grouping: “−” or “+” was included in low expression group; “++” or a higher expression was included in high expression group.

c

Bonferroni correction, α′ = 1.5 × 10−3.