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. 2016 May 21;7(25):38539–38550. doi: 10.18632/oncotarget.9533

Figure 2. SB203580 inhibits HG-induced PC cell proliferation and anti-apoptotic effects in vitro.

Figure 2

A. Examination of the proliferative capacity of PC cells after cultivation in growth media containing varying concentrations of glucose or mannitol (0-50 mM) for 24 h (n=6/group). B. Examination of PC cell proliferation after cultivation in growth media for 12, 24 or 48 h (n=6/group). *, 5 mM vs. 5 mM plus SB203580; #, 5 mM vs. 25 mM; ‡, 25 mM vs. 25 mM plus SB203580. C. Flow cytometric analysis of the PC cell cycle at 24 h. D. Cleaved caspase 3 levels in PC cells after culture with different glucose concentrations for 24 h (n=3/group). E. Flow cytometric analysis of PC cell apoptosis at 24 h. * P < 0.05, ** P < 0.01, *** P < 0.001, # P < 0.05, and ‡ P < 0.05.