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. 2016 May 21;7(25):38539–38550. doi: 10.18632/oncotarget.9533

Figure 6. SB203580 significantly inhibits tumor growth and improves the prognosis of diabetic mice with pancreatic cancer.

Figure 6

A. Examination of blood glucose levels in the different groups (n=20/group). B. All mice were weighed every 3 days after tumor transplantation. C. Survival curves of the different groups of mice over a period of up to 30 days immediately following tumor transplantation. D. Tumors in the different groups of mice were subjected to T2 WI scans 1, 2, 3 and 4 weeks after tumor transplantation. * indicates the location of the primary pancreatic tumor. E. The volumes of the tumors in the different groups at different time points were quantitatively analyzed based on the MRI data (n=6-10/group). *, WT vs. WT plus SB203580; #, WT vs. DM; and ‡, DM vs. DM plus SB203580. F. Quantitative analysis of the weight of pancreatic tumors in the different groups 4 weeks after tumor transplantation (n=6-10/group). WT: wild type; DM: diabetes mellitus. * P < 0.05, ** P < 0.01, *** P < 0.001, # P < 0.05, and ‡ P < 0.05.