The alterations of these particular cytokines and chemokines, which are normally downregulated during mid-gestation, suggest a lack of immune regulation that is typically associated with pregnancy. Cell values represent p-values obtained during adjusted logistic regression analyses. Logistic regression models were adjusted for gestational age at time of draw, maternal weight, age, race, ethnicity and country of origin. Highlighted cells represent significant logistic regression findings. Red highlighting denotes an increased risk relative to the comparison group was significantly associated with elevated mid-gestational levels of the indicated cytokines and chemokines. Blue highlighting indicates a reduced risk was significantly associated with elevated mid-gestational levels relative to the comparison group.