Table 1.
Combinations of vasopressors received by adults with septic shock
| Vasopressor | Any Use | Single Agent | First Agent* | 2 Vasopressors in Combination: 142,110 (24.3) |
||||
|---|---|---|---|---|---|---|---|---|
| VASO | NE | PHENYL | DOPA | EPI | ||||
| VASO | 100,923 (17.2) | 6,146 (1.1) | 8,959 (1.5) | — | 23,145 (4.0) | 4,320 (0.7) | 2,308 (0.4) | 1,682 (0.3) |
| NE | 335,135 (57.3) | 137,133 (23.5) | 178,717 (30.6) | — | 33,598 (5.8) | 36,414 (6.2) | 12,230 (2.1) | |
| PHENYL | 236,593 (40.5) | 102,627 (17.6) | 124,458 (21.3) | — | 13,544 (2.3) | 8,939 (1.5) | ||
| DOPA | 187,364 (32.1) | 67,765 (11.6) | 99,892 (17.1) | — | 5,930 (1.0) | |||
| EPI | 111,683 (19.1) | 26,497 (4.5) | 33,848 (5.8) | — | ||||
| Total | 584,421 (100) | 340,168 (58.2) | 445,874 (76.3) | |||||
Definition of abbreviations: DOPA = dopamine; EPI = epinephrine; NE = norepinephrine; PHENYL = phenylephrine; VASO = vasopressin.
Data presented as n (% of cohort).
*
First agent: patients who received only one vasopressor agent during hospital admission or received only one vasopressor agent on the first day of vasopressor treatment.