Figure 1.

Overlap with known genetic diseases. Lady Windermere Syndrome, characterized by idiopathic nodular bronchiectasis and nontuberculous mycobacteria, has overlapping features with several known Mendelian transmitted genetic diseases. The inner circle depicts Lady Windermere and Mrs. Erlynne (Lady Windermere’s estranged mother) from the 2002 Theater Royal production (https://www.londontheater.co.uk/reviews/lady-windermeres-fan). Overlapping circles indicate bidirectional relationships, with each of these genetic diseases having an associated high prevalence of nontuberculous mycobacteria and, in turn, Lady Windermere syndrome, having associated genetic or phenotype features from these conditions.