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. 2016 Nov 25;7:1896. doi: 10.3389/fmicb.2016.01896

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Copyright © 2016 Badhai and Das.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Schematic representation of the (A), core SXT-like ICE backbones and (B), the five hotspot regions of the three ICEs: ICEMfuInd1a, ICEMfuInd1b, and ICEMprChn1. Genes/ORFs in the five hotspots are designated as a1–a16 and b1–b25 in ICEMfuInd1a and ICEMfuInd1b, respectively (see Table 2). ICEMfuInd1a was encoded by the scaffolds: LIQF01000019.1, LIQF01000033.1, and LIQF01000014.1; ICEMfuInd1b by LIQF01000022.1, LIQF01000023.1, LIQF01000030.1, and LIQF01000009.1; and ICEMprChn1 by: AYOZ01000034.1, AYOZ01000017.1, AYOZ01000022.1, and AYOZ01000004.1. Genes/ORFs are color coded: blue, integration, and excision; yellow, DNA processing; orange, conjugative transfer system; purple, RecA-independent homologous recombination, and Umu-like mutagenic repair; green, transcriptional activator; red, transcriptional repressor; gray, other or hypothetical functions; cyan, hotspot genes; violet, gap regions; n.d, sequence not determined.