Table 1.

Phenotypes of Dab2 mutant mice.

Tissues/cell types	Phenotypes	References
Blastocysts/primitive and extraembryonic endoderm early embryos	Failed cell sorting	Morris et al., 2002b; Yang et al., 2002b, 2007; Moore et al., 2013
Kidney/proximal convoluted tubule epithelia	Mild proteinuria	Morris et al., 2002b; Moore et al., 2013
Mammary glands/epithelia	Delayed involution	Tao et al., 2014
Liver/sinusoidal endothelial cells	Increased serum cholesterol	Moore et al., 2013; Tao et al., 2016a
Adipose/Adipocytes/pericytes	Resistant to induced adipogenesis	Tao et al., 2016b
Immune system/Treg	No obvious phenotype in vivo; failed to suppress T cells	Jain et al., 2009
Tumors/multiple types	Uterine hyperproliferation, Ovarian epithelial growth, Increased tumor incidence	Yang et al., 2006; Moore et al., 2013