Table 3.
Change in stool volume and stool consistency for each group during 3-week intervention
| Baseline | Week 1 | Week 2 | Week 3 | p value† time × treatment | |
|---|---|---|---|---|---|
| Stool volume (cm3/day) | |||||
| RMD | 53.4 ± 30.1 | 69.9 ± 27.4* | 70.2 ± 27.3* | 83.4 ± 26.6* | 0.014 |
| (Δ) | (16.6 ± 32.9) | (16.8 ± 31.2) | (30.0 ± 27.4)## | ||
| Placebo | 56.4 ± 20.6 | 59.4 ± 25.0 | 64.3 ± 25.1 | 65.6 ± 23.8 | |
| (Δ) | (3.0 ± 21.4) | (7.9 ± 24.8) | (9.2 ± 20.0) | ||
| Stool consistency (score) | |||||
| RMD | 2.8 ± 1.2 | 3.0 ± 1.0 | 3.0 ± 1.2 | 3.4 ± 1.0* | n.s. |
| (Δ) | (0.3 ± 1.0) | (0.3 ± 1.2) | (0.6 ± 0.8) | ||
| Placebo | 2.8 ± 0.8 | 3.2 ± 0.8 | 3.2 ± 0.7 | 3.2 ± 0.5 | |
| (Δ) | (0.4 ± 1.0) | (0.4 ± 0.9) | (0.4 ± 0.8) | ||
Values expressed as mean ± SD (standard deviation
Δ: change from baseline to each time point; n.s.: no significant
* p < 0.05, intragroup significant difference (Bonferroni)
† p for time-by-treatment interaction was assessed by a repeated-measures ANOVA
## p < 0.01, intergroup significant differences (ANOVA)