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GPX1 rs1050450 effect on DNA strand breaks (expressed as % of DNA in comet tail) in the individuals supplemeted with selenium. A significant SNP effect was observed in the interaction with time. Data adjusted for age, sex, BMI, and baseline selenium. p values for the MANCOVA indicated in the figure. According to the particular time point analysis, a significant difference in DNA strand breaks as compared to baseline was shown during washout for ProPro homozygotes, p < 0.0001
