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. 2016 Oct 27;33(12):901–912. doi: 10.1007/s40266-016-0409-7

Table 2.

Patient demographics—controlled studies (treated patients)

Demographics Fentanyl ITS Morphine IV PCA Placebo
<65 years (N = 1264) 65–74 years (N = 325) 75–84 years (N = 158) >85 years (N = 16) <65 years (N = 931) 65–74 years (N = 234) 75–84 years (N = 135) >85 years (N = 13) <65 years (N = 250) 65–74 years (N = 44) 75–84 years (N = 20) >85 years (N = 2)
Age [mean (SEM)] 46.9 (0.29) 69.4 (0.17) 78.2 (0.20) 86.8 (0.43) 47.4 (0.34) 69.3 (0.19) 78.1 (0.22) 87.3 (0.54) 46.8 (0.69) 68.5 (0.45) 79.1 (0.60) 88.5 (1.50)
Sex
 Female [n (%)] 890 (70.4) 177 (54.5) 95 (60.1) 12 (75.0) 621 (66.7) 135 (57.7) 90 (66.7) 4 (30.8) 181 (72.4) 30 (68.2) 14 (70.0) 2 (100)
 Male [n (%)] 374 (29.6) 142 (45.5) 63 (39.9) 4 (25.0) 310 (33.3) 99 (42.3) 45 (33.3) 9 (69.2) 69 (27.6) 14 (31.8) 6 (30.0) 0
Race/ethnicity
 Caucasian [n (%)] 1027 (81.3) 291 (89.5) 148 (93.7) 16 (100) 758 (81.4) 219 (93.6) 126 (93.3) 13 (100) 208 (83.2) 42 (95.5) 19 (95.0) 2 (100)
 Black [n (%)] 149 (11.8) 17 (5.2) 5 (3.2) 0 123 (13.2) 10 (4.3) 5 (3.7) 0 20 (8.0) 2 (4.5) 0 0
 Asian [n (%)] 13 (1.0) 3 (0.9) 0 0 7 (0.8) 0 0 0 2 (0.8) 0 0 0
 Hispanic [n (%)] 46 (3.6) 10 (3.1) 4 (2.5) 0 32 (3.4) 3 (1.3) 3 (2.2) 0 13 (5.2) 0 1 (5.0) 0
 Polynesian [n (%)] 13 (1.0) 0 0 0 0 0 0 0 6 (2.4) 0 0 0
 Other [n (%)] 16 (1.3) 4 (1.2) 1 (0.6) 0 11 (1.2) 2 (0.9) 1 (0.7) 0 1 (0.4) 0 0 0
 BMI (kg/m2) [mean (SEM)] 29.4 (0.21) 28.7 (0.35) 27.5 (0.40) 25.4 (1.22) 29.8 (0.26) 29.2 (0.42) 27.1 (0.41) 25. 7 (1.18) 28.8 (0.40) 28.6 (0.88) 26.9 (1.29) 22.2 (1.32)
Surgery type [n (%)]
 Orthopedic bone 466 (36.9) 191 (58.8) 108 (68.4) 9 (56.3) 360 (38.7) 154 (65.8) 103 (76.3) 9 (69.2) 96 (38.4) 25 (56.8) 13 (65.0) 0
 Upper abdominal 76 (6.0) 12 (3.7) 9 (5.7) 0 48 (5.2) 12 (5.1) 6 (4.4) 0 7 (2.8) 4 (9.1) 0 2 (100)
 Thoracic/chest 9 (0.7) 5 (1.5) 0 0 3 (0.3) 1 (0.4) 0 0 4 (1.6) 1 (2.3) 2 (10.0) 0
 Lower abdominal 665 (52.6) 101 (31.1) 38 (24.1) 6 (37.5) 462 (49.6) 63 (26.9) 23 (17.0) 2 (15.4) 142 (56.8) 12 (27.3) 4 (20.0) 0
 Other 48 (3.8) 16 (4.9) 3 (1.9) 1 (6.3) 58 (6.2) 4 (1.7) 3 (2.2) 2 (15.4) 1 (0.4) 2 (4.5) 1 (5.0) 0

BMI body mass index, ITS iontophoretic transdermal system, IV PCA intravenous patient-controlled analgesia, SEM standard error of measure