Table 2. Univariate and Multivariate Analysis of Factors Predictive of a Clinical Remission.
| Variables | Remission (n=48, %) | Not remission (n=47, %) | Type of analysis | |||
|---|---|---|---|---|---|---|
| Univariate | Multivariate | |||||
| OR (95% CI) | p value | OR (95% CI) | p value | |||
| Age (yr) | ||||||
| Median (range) | 45.1 (17–81) | 43.7 (12–75) | 0.714 | 1.002 (0.973–1.032) | 0.906 | |
| Gender | ||||||
| Male/female | 21/27 (43.8/56.2) | 26/21 (55.3/44.7) | 0.388 | 0.710 (0.278–1.813) | 0.474 | |
| Azathioprine medication | ||||||
| Yes/no | 12/36 (25.0/75.0) | 10/37 (21.3/78.7) | 0.667 | 0.878 (0.308–2.502) | 0.807 | |
| Disease extension | ||||||
| Proctitis | 6 | 4 | 1 | 1 | ||
| Left-sided colitis | 14 | 11 | 1.71 (0.439–6.699) | 0.438 | 2.669 (0.523–13.634) | 0.238 |
| Extensive | 28 | 32 | 1.18 (0.265–5.237) | 0.829 | 1.848 (0.384–8.889) | 0.444 |
| ANCA | ||||||
| Positive | 10 (29.4) | 16 (40) | 1.60 (0.605–4.228) | 0.343 | ||
| Negative | 24 (70.6) | 24 (60) | 1 | |||
| Unknown | 14 | 7 | ||||
| Disease duration (months) | ||||||
| Median (range) | 78.17 (4–300) | 58.34 (3–204) | 0.109 | |||
| 4 week treatment effect | ||||||
| Disease activity | ||||||
| Mild/moderate | 22/25 | 11/33 | 2.64 (1.083–6.435) | 0.033 | 2.64 (1.083–6.435) | 0.033 |
| Mild/moderate+severe | 22/26 | 11/36 | 2.77 (1.146–6.691) | 0.024 | 2.64 (1.083–6.435) | 0.033 |
| Mild/severe | 22/1 | 11/3 | 2.45 (0.747–8.036) | 0.139 | ||
| Moderate/severe | 25/1 | 33/3 | 2.27 (0.223–23.174) | 0.488 | ||
| Mild+moderate/severe | 47/1 | 44/3 | 3.21 (0.321–31.970) | 0.321 | ||
ANCA, anti-neutrophil cytoplasmic antibodies.