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. 2016 Nov 25;7:455. doi: 10.3389/fphar.2016.00455

FIGURE 1.

FIGURE 1

Macroscopic and microcosmic observation. (A) Typical images of an intact colon. A1, A2, A3, and A4, respectively, represent the Normal, 2, 4, 6-trinitrobenzene sulfonic acid (TNBS), TNBS + Curcumin, and TNBS + Mesalazine animal groups. (B) Macrography of the opened colon. B1, B2, B3, and B4, respectively, represent the Normal, TNBS, TNBS + Curcumin, and TNBS + Mesalazine animal groups. (C) Body weight. (D) Colonic weight. (E) Weight index of the colon. (F) Typical histological images stained by HE, f1–4: Bar = 40 μm, f5–8: Bar = 100 μm. (G) Colonic length. (H) Histological scores. Data were presented as mean ± SEM (n = 10). ∗p < 0.05 and ∗∗p < 0.01 versus the Normal group; #p < 0.05 and ##p < 0.01 versus the TNBS group.