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. 2016 Oct 14;50(6):426–435. doi: 10.4132/jptm.2016.07.19

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© 2016 The Korean Society of Pathologists/The Korean Society for Cytopathology

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Fig. 3. — Increased irregularity of follicles in the aged mouse thyroid. Hematoxylin and eosin (H&E)–stained sections of thyroid from 15-month-old (A) and 30-month-old (B) mice. (C) Oncocytic change in the follicular cells of aged mouse thyroid stained with H&E. (D) Sections of 30-month-old mouse thyroid stained with anti–translocase of the outer mitochondrial membrane (TOM20) antibody visualized by 3,3'-diaminobenzidine. Non-oncocytic follicular cells are weak for TOM20 (left panels), while oncocytic follicular cells are strongly TOM20-positive (right panels). Tg, thyroglobulin.