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. 2016 Oct 14;50(6):426–435. doi: 10.4132/jptm.2016.07.19

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© 2016 The Korean Society of Pathologists/The Korean Society for Cytopathology

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Fig. 5. — Sections of thyroid from elderly females highlighting various morphological changes. (A) Size variation and enlargement of the follicles. (B) Increased irregularity of follicles and Sanderson’s polsters in the wall of large follicles. (C) A large thyroglobulin (Tg) globule (right upper image) and numerous small fragmented Tg globules (right lower image) in the follicular lumen. (D) Oncocytic change in the follicular cells and in those with Sanderson’s polsters. (E) Irregularly dilated follicles lacking colloid. (F) Fibrosis of the extracellular matrix. (G) Fatty infiltration in the extracellular matrix.