TABLE 1.
Population characteristics of children and young adults with asthma who underwent genotyping for TRPV1 polymorphisms
LTRA, leukotriene receptor antagonist; BMI, body mass index.
| Variable | Population value | eAT population value |
|---|---|---|
| Total subjects (n) | 1569 | 74 |
| Subjects utilizing a short acting bronchodilator (n (%)) | 1421 (90.6) | 73 (98.6) |
| Subjects treated with a long acting β-agonist (n (%)) | 12 (7.6) | 0 (0) |
| Subjects treated with an inhaled glucocorticoid (n (%)) | 958 (61.1) | 63 (85.1) |
| Subjects treated with other asthma drug (LTRA, anti-inflammatory, etc.) (n (%)) | 451 (28.7) | 24 (32.4) |
| Age, mean ± S.D. (years) | 8.84 ± 4.26 | 6.98 ± 3.31 |
| Sex (n (%)) | ||
| Male | 938 (59.9) | 43 (58.1) |
| Female | 627 (40.1) | 31 (41.9) |
| Race/ethnicity (n (%)) | ||
| American Indian/Alaskan Native | 15 (1.0) | 1 (1.4) |
| Asian | 13 (0.8) | 1 (1.4) |
| Black/African American | 57 (3.6) | 2 (2.7) |
| Native Hawaiian/Pacific Islander | 44 (2.8) | 3 (4.1) |
| White/Caucasian | 1101 (70.7) | 49 (67.1) |
| Unknown/not reported | 328 (21.1) | 17 (23.3) |
| Ethnicity (n (%)) | ||
| Hispanic | 308 (19.7) | 15 (20.5) |
| Non-Hispanic | 824 (52.9) | 25 (34.2) |
| Unknown, not reported | 427 (27.4) | 33 (45.2) |
| Weight, mean ± S.D. (kg) | 36.3 ± 21.9 | 27.1 ± 15.8 |
| Height, mean ± S.D. (cm) | 131.5 ± 25.2 | 120.8 ± 22.9 |
| BMI | 19.7 ± 9.1 | 20.6 ± 16 |
| Asthma control score, mean ± S.D. | 4.1 ± 3.3 | 4.9 ± 3.8a |
a Statistically different compared with the overall population (two-tailed p = 0.0432) using an unpaired t test.