TABLE 2.
The minor allele and genotype frequencies for I315M, T469I, and I585V variants in the study cohort
Global minor allele frequency (MAF) and sample size are as reported by the 1000 genomes project.
| TRPV1 SNP | Global MAF | Observed MAF | Wild-type frequency | Heterozygote frequency | Variant frequency |
|---|---|---|---|---|---|
| % | % | % | % | % | |
| I315M | 26.7 (n = 1335) | 25.3 | 56.3 | 36.7 | 7.0 |
| I315 M eAT | 37.0 | 37.3 | 50.8 | 11.9 | |
| T469I | 37.8 (n = 1893) | 37.4 | 40.1 | 45.0 | 14.8 |
| T469I eAT | 49.0 | 26.7 | 48.3 | 25.0 | |
| I585V | 31.8 (n = 1591) | 36.7 | 40.2 | 46.1 | 13.7 |
| I585V eAT | 52.0 | 18.6 | 59.3 | 22.0 |