Skip to main content
. 2016 Nov 25;6:37345. doi: 10.1038/srep37345

Figure 7. The effects of treatment on allopregnanolone in HFD-STZ rats.

Figure 7

The decreased levels allopregnanolone were reversed by AC-5216 in the prefrontal cortex (A) and hippocampus (B) but not in serum (C). However, the effects of AC-5216 were totally blocked by PK11195 in the prefrontal cortex (D) and hippocampus (E), but not in serum (F). #p < 0.05, ##p < 0.01 vs. vehicle-treated HFD-STZ (−) group; *p < 0.05, **p < 0.01 vs. vehicle-treated HFD-STZ (+) group; $p < 0.05, $$p < 0.01 vs. AC-5216 (1 mg/kg, i.p.) group (n = 6).