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. 2016 Nov 25;6:37499. doi: 10.1038/srep37499

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a. HUVECs co-cultured with untransfected HepG2 b. HUVECs co-cultured with overexpression–LV-CON transfected HepG2 c. HUVECs co-cultured with overexpression–LV-BMP2 HepG2 d. HUVECs co-cultured with untransfected HepG2 e. HUVECs co-cultured with LV-SH-CON HepG2 f. HUVECs co-cultured with LV-SH-BMP2 HepG2 Notes: BMP-2: Bone morphogenetic protein 2; HUVEC: human umbilical vein endothelial cell; LV-SH-BMP2: lentivirus vectors expressing small hairpin RNA against BMP-2 gene. *Indicates P < 0.05 as compared with other groups.