Table 1. Demographics of Study Population in the study of iTRAQ.

Stage	Variables	VSD-PAH†	VSD†	ASD-PAH†	ASD†	Mix-PAH†	Mix†	Controls†
iTRAQ*	Number	20	20	20	20	20	20	20
	Sex (M/F)‡	12/8	10/10	10/10	7/13	12/8	11/9	13/7
	Age (years)	4.0 ± 0.8	3.7 ± 0.5	9.3 ± 2.2§	7.1 ± 1.5||	2.7 ± 0.7	3.8 ± 0.6	3.5 ± 0.7
	PASP (mmHg)¶	68.65 ± 3.04	N/A¶	47.47 ± 2.16	N/A¶	60.71 ± 4.55	N/A¶	N/A¶

^*iTRAQ = isobaric tags for relative and absolute quantitation;

^†VSD-PAH = ventricular septal defect with PAH; VSD = ventricular septal defect; ASD-PAH = atrial septal defect with PAH; ASD = atrial septal defect; Mix-PAH = mixed type heart defects (two or more defects of VSD, ASD and PDA) with PAH; Mix = mixed type heart defects (two or more defects of VSD, ASD and PDA) without PAH;

^‡M = male, F = female;

^§,*P < 0.05 vs. Controls;

^||,*P < 0.05 vs. Controls;

^¶PASP = Pulmonary arterial systolic pressure; N/A = not applicable.