Table 2. Demographics of Study Population in the study of ELISA.
| Stage | Variables | VSD-PAH† | VSD† | ASD-PAH† | ASD† | Mix-PAH† | Mix† | Controls† |
|---|---|---|---|---|---|---|---|---|
| ELISA | Number | 40 | 21 | 21 | 21 | 21 | 21 | 37 |
| (CPSI)* | Sex (M/F)‡ | 21/19 | 10/11 | 8/13 | 9/12 | 6/15 | 8/13 | 20/17 |
| Age (years) | 4.4 ± 0.8 | 5.0 ± 0.8 | 9.3 ± 2.4§ | 4.1 ± 0.7 | 2.2 ± 0.4 | 6.8 ± 1.5|| | 3.8 ± 0.6 | |
| PASP (mmHg)¶ | 65.05 ± 3.35 | N/A¶ | 56.43 ± 3.44 | N/A¶ | 78.60 ± 4.59 | N/A¶ | N/A¶ | |
| ELISA | Number | 11 | 11 | 11 | 11 | 11 | 11 | 16 |
| (CFHR2)* | Sex (M/F)‡ | 7/4 | 6/5 | 5/6 | 4/7 | 3/8 | 5/6 | 9/7 |
| Age (years) | 3.1 ± 0.7 | 4.8 ± 1.1 | 9.5 ± 3.0# | 4.4 ± 1.1 | 1.7 ± 0.3 | 6.5 ± 1.6** | 3.0 ± 0.5 | |
| PASP (mmHg)¶ | 46.3 ± 1.69 | N/A¶ | 62.64 ± 5.75 | N/A¶ | 79.32 ± 7.52 | N/A¶ | N/A¶ |
*CPSI = Carbamoyl-phosphate Synthetase I; CFHR2 = complement Factor H-related Protein 2;
†VSD-PAH = ventricular septal defect with PAH; VSD = ventricular septal defect; ASD-PAH = atrial septal defect with PAH; ASD = atrial septal defect; Mix-PAH = mixed type heart defects (two or more defects of VSD, ASD and PDA) with PAH; Mix = mixed type heart defects (two or more defects of VSD, ASD and PDA) without PAH;
‡M = male, F = female;
§,*P < 0.05 vs. ASD; **P < 0.01 vs. Controls;
||,**P < 0.01 vs. Mix-PAH; *P < 0.05 vs. Controls;
#,*P < 0.05 vs. Controls;
**P < 0.01 vs. Mix-PAH;
¶PASP = Pulmonary arterial systolic pressure; N/A = not applicable.