Table 3. Differential proteins expressed in all 6 patient groups with CHD/CHD-PAH compared to the control, identified by iTRAQ (See Data file S2 for all differential proteins identified by iTraq study).
| Accession | Protein | Score | Coverage | Unique Peptides | Peptides | VSD-PAH | VSD | ASD-PAH | ASD | Mix-PAH | Mix | Control |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 13937839 | SAA1 protein | 249.56 | 54.10% | 2 | 5 | 0.346 | 0.566 | 0.47 | 0.761 | 0.375 | 0.306 | 1 |
| 1064908 | complement Factor H-related Protein 2* | 222.48 | 31.28% | 3 | 6 | 0.497 | 0.612 | 0.601 | 0.883 | 0.641 | 0.575 | 1 |
| 3152372 | anti-FactorVIII scFv | 537.51 | 64.29% | 1 | 10 | 0.499 | 0.751 | 0.5 | 0.637 | 0.538 | 0.726 | 1 |
| 56378229 | Carbamoyl-phosphate synthetase I* | 22.22 | 4.09% | 1 | 1 | 0.503 | 0.742 | 0.47 | 0.681 | 0.399 | 0.544 | 1 |
| 47124510 | APCS protein | 30.38 | 23.91% | 1 | 1 | 0.532 | 0.618 | N/A† | N/A† | 0.779 | 0.676 | 1 |
| 1769552 | von Willebrand factor | 27.48 | 3.73% | 1 | 1 | 0.582 | 0.201 | 1.223 | 0.6 | 0.785 | 0.606 | 1 |
| 74355107 | BRF1 protein | 30.09 | 4.97% | 1 | 1 | 0.606 | N/A† | 0.796 | 0.714 | 0.815 | 0.828 | 1 |
| 54304028 | glyceraldehyde-3-phosphate dehydrogenase | 45.44 | 17.44% | 1 | 1 | 0.679 | 0.675 | 0.657 | 0.611 | 0.603 | 0.629 | 1 |
| 11122875 | glycosylphosphatidylinositol phospholipase D | 137.2 | 8.32% | 3 | 3 | 1.685 | 1.28 | 1.765 | 1.804 | 1.674 | 1.446 | 1 |
| 20377087 | intestinal lactoferrin receptor | 171.75 | 29.07% | 7 | 7 | 1.694 | 1.393 | 1.218 | 1.212 | 1.508 | 1.446 | 1 |
*Candidate proteins for validation.
†N/A represents data are not available.