Table 1.
Patient and tumor characteristics relative to chemotherapy status in all patients
| Characteristics | Total, n (%) | Chemotherapy, n (%) |
p value | |
|---|---|---|---|---|
| no | yes | |||
| Age, years | ||||
| <50 | 93 (100) | 32 (34.4) | 61 (65.6) | <0.001 |
| 50–65 | 1,828 (100) | 972 (53.2) | 856 (46.8) | |
| >65 | 1,997 (100) | 1,449 (72.6) | 548 (27.4) | |
| Total, n | 3,918 | 2,453 | 1,465 | |
| BMI, kg/m2 | ||||
| <20 | 139 (100) | 89 (64.0) | 50 (36.0) | 0.160 |
| 20–25 | 1,248 (100) | 801 (64.2) | 447 (35.8) | |
| 25–30 | 1,509 (100) | 937 (62.1) | 572 (37.9) | |
| >30 | 1,005 (100) | 617 (61.4) | 388 (38.6) | |
| Total, n | 3,901 | 2,444 | 1,457 | |
| ECOG | ||||
| 0 or 1 | 3,770 (100) | 2,356 (62.5) | 1,414 (37.5) | 0.353 |
| >1 | 151 (100) | 100 (66.2) | 51 (33.8) | |
| Total, n | 3,921 | 2,456 | 1,465 | |
| Grading | ||||
| 1 | 586 (100) | 511 (87.2) | 75 (12.8) | <0.001 |
| 2 | 2,688 (100) | 1,711 (63.7) | 977 (36.3) | |
| 3 | 623 (100) | 221 (35.5) | 402 (64.5) | |
| Total, n | 3,897 | 2,443 | 1,454 | |
| HER2 | ||||
| Negative | 3,402 (100) | 2,224 (65.4) | 1,178 (34.6) | <0.001 |
| Positive | 491 (100) | 208 (42.4) | 283 (57.6) | |
| Total, n | 3,893 | 2,432 | 1,461 | |
| Concomitant medication, n | ||||
| 0 | 1,685 (100) | 989 (58.7) | 696 (41.3) | <0.001 |
| 1 | 605 (100) | 378 (62.5) | 227 (37.5) | |
| 2 | 431 (100) | 274 (63.6) | 157 (36.4) | |
| 3 | 281 (100) | 165 (58.7) | 116 (41.3) | |
| ≥4 | 922 (100) | 652 (70.7) | 270 (29.3) | |
| Total, n | 3,924 | 2,458 | 1,466 | |
| Concomitant diseases, n | ||||
| 0 | 1,328 (100) | 772 (58.1) | 556 (41.9) | < 0.001 |
| 1 | 1,059 (100) | 647 (61.1) | 412 (38.9) | |
| 2 | 745 (100) | 483 (64.8) | 262 (35.2) | |
| 3 | 426 (100) | 290 (68.1) | 136 (31.9) | |
| ≥4 | 366 (100) | 266 (72.7) | 100 (27.3) | |
| Total, n | 3,924 | 2,458 | 1,466 | |
BMI = Body mass index; ECOG = Eastern Cooperative Oncology Group.