Table 2.

Criteria and cutoff points for the diagnosis of metabolic syndrome in adolescents

Criterion	Cook et al., 2003 [15]	de Ferranti et al., 2004 [16]	Ford et al., 2007 [17]	Agudelo and Arias, 2008 [18]	IDF consensus definition, 2007 [19]
Triglycerides/HDL-C	≥110 mg/dl; ≤40 mg/dl	≥100 mg/dl; <50 mg/dl	≥110 mg/dl; ≤40 mg/dl	≥110 mg/dl; ≤40 mg/dl	≥150 mg/dl; <40 mg/dl
		<45 mg/dl in 15- to 19-year-old males
Fasting glucose	≥110 mg/dl	≥110 mg/dl	≥100 mg/dl	≥100 mg/dl	≥100 mg/dl
Blood pressure, mm Hg	≥90th percentile; by age, gender, and height	≥90th percentile; by age, gender, and height	≥90th percentile; by age, gender, and height	≥90th percentile; by age, gender, and height	SBP ≥ 130 mm Hg; DBP ≥ 85 mm Hg
Waist circumference	≥90th percentile; by age and gender	>75th percentile; by age and gender	≥90th percentile; by age and gender	≥95th percentile	≥90th percentile; by age and gender
BMI	none	none	none	none	none
Metabolic syndrome diagnosis	presence of three or more criteria	presence of three or more criteria	presence of three or more criteria	presence of three or more criteria	high waist circumference + two other criteriaa

^aAdolescents > 16 years; waist circumference in men > 102 cm and in women > 88 cm; triglycerides > 150 mg/dl; HDL-C in men < 40 mg/dl and in women < 50 mg/dl; blood pressure ≥ 130 / 85 mm Hg or treatment for previously diagnosed hypertension; glucose ≥ 100 mg/dl or diagnosed for type 2 diabetes mellitus (T2DM).

IDF = International Diabetes Federation; BMI = body mass index; HDL-C = high-density lipoprotein cholesterol; SBP = systolic blood pressure; DBP = diastolic blood pressure.