Table 1.
Demographics, risk factors and baseline characteristics in groups 1 and 2 and healthy controls
Group 1 (n = 10) | Group 2 (n = 10) | P value | Healthy controls (n = 20) | |
---|---|---|---|---|
Male | 10 | 10 | 12 | |
Female | 2 | 3 | 8 | |
Age, mean ± SD, years | 48.6±7.1 | 48.1±9.1 | 0.24 | 49.6±5.6 |
Average time to stroke onset, months | 11.6 | 10.5 | ||
Risk factors | ||||
Hypertension | 7 (70%) | 6 (60%) | 0.15 | 12 (60%) |
Diabetes mellitus | 5 (50%) | 3 (30%) | 0.87 | 6 (30%) |
Hypercholesterolemia | 6 (60%) | 4 (40%) | 0.56 | 10 (50%) |
Smoking | 4 (40%) | 4 (40%) | 0.49 | 13 (65%) |
Alcohol consumption | 3 (30%) | 2 (20%) | 1.0 | 5 (25%) |
Tobacco abuse | – | – | 0.58 | 3 (15%) |
Coronary artery disease | 5 (50%) | 6 (40%) | – | 5 (25%) |
Ischemic stroke (subtype) | ||||
LA atherosclerosis | 4 (40%) | 4 (40%) | 0.67 | |
CE | 4 (40%) | 1 (10%) | 0.35 | |
SA occlusion | 2 (20%) | 3 (30%) | 0.21 | |
Others | – | 2 (20%) | 0.81 | |
Laboratory parameters | ||||
Baseline | ||||
VEGF | 366.2±78.6 pg/ml | 370.5±91.1ng/ml | 0.42 | |
BDNF | 18.7±6.6 pg/ml | 16.1±7.6 ng/ml | 0.56 | |
8 Weeks | ||||
VEGF | 453.5±89.1pg/ml | 408.4±98.4ng/ml | 0.96 | |
BDNF | 32.8±9.2 pg/ml | 27.3±8.9 ng/ml | 0.78 |