Figure S5.
Increased cecal bile acid concentration points to an increased fat oxidation in GF mice. Correlation between cecal bile acid concentration and respiratory exchange ratio measured during basal metabolic rate recordings and represented as the mean of fasted animals following 4 wks of feeding CD, PHFD or LHFD. SPF CD: n = 5; SPF PHFD: n = 5; SPF LHFD: n = 5; GF CD: n = 5; GF PHFD: n = 4; GF LHFD: n = 5. Linear regression of GF or SPF C57BL/6N mice was calculated irrespective of the diet. GF: r2 = 0.26, p < 0.05; SPF: r2 = 0.22, p = ns.