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. 2016 Nov 25;9:127. doi: 10.1186/s13045-016-0361-3

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — MAGL promotes the progression of HCC by enhancing EMT. a The cellular morphology of HCC cell lines (HepG2-vector, HepG2-MAGL, HCCLM3-vector, and HCCLM3-shMAGL). b Western blot assay revealed the expression of epithelial and mesenchymal markers, as well as the transcription factors, in HCC cells with different MAGL expression (HepG2-vector, HepG2-MAGL, HCCLM3-vector, and HCCLM3-shMAGL). c–g qRT-PCR analysis of E-cadherin, N-cadherin, Vimentin, Snail, Twist levels in the indicated cell lines. h Representative immunostaining images of EMT markers using serial sections of tumor samples. Scale bar, 50 μm. Data represent the mean + SD. *P < 0.05, **P < 0.01, and ***P < 0.001