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. 2016 Nov 25;8:50. doi: 10.1186/s13195-016-0217-7

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — Angiotensin-converting enzyme 2 (ACE-2) expression in mid-frontal cortex in Alzheimer’s disease. a and b ACE-2 displayed strong capillary labelling (black arrows) and abundant perivascular labelling of larger arterioles (scale bar = 100 μm). Shown in b at higher magnification (scale bar = 50 μm). b and c ACE-2 was present in astrocytes (scale bar = 50 μm). d Pre-adsorption of ACE-2 antibody with recombinant human ACE-2 abolished labelling, confirming antibody specificity (scale bar = 100 μm)