Table 2.

Problems Observed in Aging or Older People with A-T

• Ballistic, retropulsive or jerky movements
• Sensory and motor neuropathy
• Brain telangiectasia (observed by MRI)
• Restrictive lung disease
• Elevated cholesterol and triglyceride levels
• Glucose intolerance and diabetes
• Liver abnormalities (e.g. fatty liver; non-alcoholic cirrhosis; elevated serum transaminases)
• Changes in the types of malignancies (there is an increased incidence for both lymphoid and solid tumors)
• Osteoporosis/osteopenia and low vitamin D levels
• Postural scoliosis and progressive foot deformities
• Gastroesophageal reflux (especially if reflux was an issue in infanthood)
• Early menopause
• Depression
• Aging parents and caregivers