Locomotor activity (distance traveled, cm) in adolescent and adult Wistar rats exposed to 5 days of restraint stress (120 min per day), or non-stressed during postnatal days 30–34 or 70–74, for each age, respectively. Two hours following termination of the last stress session on postnatal day 34 or 74, the rats were given ethanol (2.5 g/kg, i.g.) or its vehicle (tap water) before locomotor activity was measured during 5–9 min post-administration time in an open field. The asterisk sign indicates a significant difference between adolescents given ethanol vs. those given vehicle (p < 0.05). The vertical bars indicate SEM.