Fig. 6. Sensitivity to the sedative and narcotic effects of ethanol in adolescent and adult rats.
Loss of righting reflex (sec) and sleep time (sec) after 4.0 or 4.5 g/kg ethanol (i.p.) in adolescent (panels A and B) and adult (panels C and D) Sprague-Dawley rats as a function of stress treatment experienced during postnatal days 30–34 or 70–74 (5 days of restraint stress [120 min per day] or non-stressed). The asterisk indicates a significant main effect of ethanol dose on sleep time. The pound sign indicates a significant main effect of prior stress exposure on ethanol-induced sleep time in adults. Vertical lines indicate SEM.
