Table 3.

Significant bacterial genera between benign and endometrial cancer cohorts

Combined q < 0.10	Value	Standard error	Degrees of freedom	t value	p value	q value	Test
Firmicutes; Anaerostipes	3.4	0.795	25	4.3	0.0002	0.017	Presence/absence
Firmicutes; ph2	3.1	0.829	25	3.7	0.0010	0.031	Presence/absence
Spirochaetes; Treponema	3.9	1.066	25	3.7	0.0011	0.031	Presence/absence
Actinobacteria; Atopobium	2.5	0.707	25	3.5	0.0017	0.036	Presence/absence
Bacteroidetes; Bacteroides	1.1	0.332	25	3.3	0.0026	0.044	Counts
Proteobacteria; Arthrospira	3.6	1.150	25	3.1	0.0044	0.062	Presence/absence
Firmicutes; Dialister	1.2	0.405	25	3.0	0.0061	0.073	Presence/absence
Firmicutes; Peptoniphilus	1.4	0.494	25	2.9	0.0074	0.075	Presence/absence
Firmicutes; 1-68	1.3	0.465	25	2.9	0.0080	0.075	Presence/absence
Firmicutes; Ruminococcus	0.9	0.319	25	2.8	0.0109	0.082	Counts
Bacteroidetes; Porphyromonas	1.8	0.664	25	2.7	0.0111	0.082	Presence/absence
Firmicutes; Anaerotruncus	1.3	0.477	25	2.7	0.0117	0.082	Presence/absence

Significant bacterial genera between benign and endometrial cancer cohorts in the vaginal, cervical, and endometrial microbiome as determined by generalized mixed effect model (FDR q < 0.10). All genera are enriched in the endometrial cancer cohort